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Therapy evaluation by phase-contrast MRI for pulmonary hypertension: Multicenter prospective exploratory study

Therapy evaluation by phase-contrast MRI for pulmonary hypertension: Multicenter prospective exploratory study - Therapy evaluation by PCMRI for PH

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000027960
Enrollment
50
Registered
2017-07-01
Start date
2016-12-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulmonary hypertension

Interventions

We perform MR exam two times of plans before and 3-6 months after therapy.

Sponsors

Graduate School of Medical Science, University of the Ryukyus Department of Radiology
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1.The patients to perform pharmacotherapy with the vasodilator in for pulmonary hypertension in hospital attached to the University of Ryukyu School of Medicine, Kanagawa circulatory organ respiratory disease center, Sapporo Medical College hospital during a period with December, 2018 from December, 2016. 2.Written informed consent is obtained.

Exclusion criteria

Exclusion criteria: 1.MRI contraindication, relative contraindicated matter pertinence person (claustrophobia, the pregnant woman, the patients implanted metal in the body, the patients with the tattoo) 2.The patients who cannot keep rest 30 minutes or more with a dorsal position 3.Chronic thromboembolic pulmonary hypertension

Design outcomes

Primary

MeasureTime frame
The change of pulmonary flow measured by PC-MRI in the before and after therapy

Secondary

MeasureTime frame
The change of the measurement values of PC-MRI:Mean velocity, Acceleration time, Peak velocity, maximal change in the flow rate/Acceleration volume, Cardiac index Correlation between pulmonary flow and mean pulmonary arterial pressure and 6 minutes distance walk.

Countries

Japan

Contacts

Public ContactJunji Jyunji

Graduate School of Medical Science, University of the Ryukyus Department of Radiology

es4d8yd@gmail.com098-895-1162

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026