Skip to content

Effect of eXercise and Oral Nutritional supplement on prevention of frailty in hypertensive patients with stroke or chronic kidney diseases

Effect of eXercise and Oral Nutritional supplement on prevention of frailty in hypertensive patients with stroke or chronic kidney diseases - Effect of eXercise and Oral Nutritional supplement on prevention of frailty in hypertensive patients (EXON)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000027939
Enrollment
150
Registered
2017-07-01
Start date
2017-07-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertensive patients with stroke or chronic kidney disease

Interventions

Exercise-only group Exercise(stretching and resistance) 2 per week Periods: 3 months Exercise plus oral nutritional supplement group Exercise(stretching and resistance) and consume nutritional su

Sponsors

Asahikawa Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who meet all of the following criteria at institutions participating in the study (1) Patients diagnosed with hypertension, regardless of treatment with an antihypertensive drug (2) Male or female patients at least 40 years old and less than 85 years old (3) Patients with stroke or patients with chronic kidney disease (dipstick proteinuria 1+ and above or eGFR 30-60 ml/min/1.73m2) (4) Patients who have consented in writing

Exclusion criteria

Exclusion criteria: Patients who meet any of the following criteria are not included in the study subjects (1) Patients with myocardial infarction, unstable angina, or a peripheral artery disease that has developed within the last 6 months (2) Patients with acute-phase heart failure (3) Patients being treated for malignant tumors (4) Patients who have undergone a surgery within the last 6 months (5) Patients who have allergies to milk or soy (6) Patients with severe renal dysfunction (eGFR less than 30 ml/min/1.73m2) (7) Other patients that an investigator finds inappropriate to be included in the study population

Design outcomes

Primary

MeasureTime frame
Changes in body composition and frailty

Secondary

MeasureTime frame
1) Blood pressure (outpatient measurement at hospital visits), home blood pressure 2) Renal function 3) Motor function

Countries

Japan

Contacts

Public ContactNaoki Nakagawa

Asahikawa Medical University Division of Cardiology, Nephrology, Pulmonology and Neurology, Department of Internal Medicine

naka-nao@asahikawa-med.ac.jp0166-68-2442

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026