Association of intraoperative HES130/0.4 and postoperative complications in dialysis-dependent patients :A retrospective cohort study using DPC database

Association of intraoperative HES130/0.4 and postoperative complications in dialysis-dependent patients :A retrospective cohort study using DPC database - Association of intraoperative HES130/0.4 and postoperative complications for dialysis-dependent patients.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000027895

Enrollment

4000

Registered

2017-06-30

Start date

2017-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dialysis-dependent patients who underwent surgery

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1)Dialysis-dependent patients who underwent surgery from January 2014 to December 2016 (2)Patients 18 years or older (3)Patients who underwent surgery under general anesthesia

Exclusion criteria

Exclusion criteria: (1)Patients who received dextran or HES70/0.5 (2)Patients who received HES130/0.4 during the period between 7 days before surgery and the day before surgery (3)Patients who died within 2 days after surgery (4)Patients who underwent multiple surgeries (during the period of 30 days before and 30 days after surgery) (5)Patients who received HES130/0.4 only before and/or after surgery on the day of surgery

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative complications (Myocardial infarction, congestive heart failure, arrhythmia, hypotension, pneumonia, cerebrovascular accident, surgical site infection, postoperative bleeding, sepsis, emergency dialysis (day of surgery), postoperative mortality (within 30 days after surgery) )	—

Secondary

Measure	Time frame
(1)Number of postoperative complications (2)ICU admission (3)Length of postoperative hospital stay (4)Medical expenditure during hospital stay (5)Blood clotting ability (platelet count, PT-INR, APTT)	—

Countries

Japan

Contacts

Public ContactSatoru Kamoshita

Otsuka Pharmaceutical Factory, Inc. Applied Clinical Development Department

kamoshitas@otsuka.jp03-5217-5954

Outcome results