relation between xanthine oxidoreductase and coronary plaque or endotherial function

relation between xanthine oxidoreductase and coronary plaque or endotherial function - relation between xanthine oxidoreductase and coronary plaque or endotherial function

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000027855

Enrollment

Registered

2017-06-26

Start date

2017-06-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary artery disease

Interventions

1. blood test 2. intravascular ultrasonography 3. endothelial function test

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patient who will undergo percutaneous coronary intervention with NIRS-IVUS in our hospital

Exclusion criteria

Exclusion criteria: 1. patients undergoing hemodialysis 2. patients taking inhibitor of xanthine oxidoreductase 3. patients who are not eligible by the investigators

Design outcomes

Primary

Measure	Time frame
Relation between xanthine oxidoreductase reactivity and coronary lipid plaque with NIRS-IVUS	—

Secondary

Measure	Time frame
1. Relation between xanthine oxidoreductase reactivity and endothelial function with Endo-PAT 2. Distribution of xanthine oxidoreductase reactivity in coronary artery disease 3. Relation between xanthine oxidoreductase reactivity and uric acid 4. Relation between xanthine oxidoreductase reactivity and coronary plaque volume 5. Relation between purine bodies (hypoxanthine, xanthine) and coronary lipid plaque 6. Relation between purine bodies (hypoxanthine, xanthine) and endothelial function 7. Relation between uric acid and coronary plaque or endothelial function	—

Measure

Time frame

1. Relation between xanthine oxidoreductase reactivity and endothelial function with Endo-PAT 2. Distribution of xanthine oxidoreductase reactivity in coronary artery disease 3. Relation between xanthine oxidoreductase reactivity and uric acid 4. Relation between xanthine oxidoreductase reactivity and coronary plaque volume 5. Relation between purine bodies (hypoxanthine, xanthine) and coronary lipid plaque 6. Relation between purine bodies (hypoxanthine, xanthine) and endothelial function 7. Relation between uric acid and coronary plaque or endothelial function

—

Countries

Japan

Contacts

Public ContactYuichi Saito

Chiba University Hospital Department of Cardiovascular Medicine

policemaccho@yahoo.co.jp043-222-7171

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026