Evaluation of change in blood glucagon levels in response to orally glucose loading and food intake

Evaluation of change in blood glucagon levels in response to orally glucose loading and food intake - Measurement of blood glucagon levels in glucose tolerance and meal tolerance test

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000027852

Enrollment

Registered

2017-06-30

Start date

2017-06-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes mellitus

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Normal subjects 1) 20 - 69 years old 2) HbA1c is less than 6.2% 3) person who do not regularly use medicine Diabetes patients 1) 20 - 69 years old 2) patients who are not receiving medication for diabetes

Exclusion criteria

Exclusion criteria: 1) abnormal in liver or renal function test 2) a woman within 12 weeks expected to give birth 3) impaired cardiopulmonary function 4) anemia symptoms 5) chronic or acute infections according to the judgment of doctor 6) persons who are participating in other clinical trials at the start of this study 7) subjects judged by investigator as inappropriate

Design outcomes

Primary

Measure	Time frame
The time course (0, 30, 60, 120, 180 min after loading) of blood glucagon levels in diabetes patients in response to glucose loading or food intake will be compared with those in normal glucose tolerant subjects.	—

Secondary

Measure	Time frame
In addition, blood glucose, insulin, and incretin levels will be measured and analyzed in accordance with kinetic changes in blood glucagon levels.	—

Countries

Japan

Contacts

Public ContactTadahiro Kitamura

Institute for Molecular and Cellular Regulation, Gunma University Metabolic Signal Research Center

hitotaisho-ciru@ml.gunma-u.ac.jp+81-27-220-8845

Outcome results