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Investigating biomarkers for development of atopic dermatitis in early childhood using maternal-infant hair-related microRNA

Investigating biomarkers for development of atopic dermatitis in early childhood using maternal-infant hair-related microRNA - Hair-related microRNA effects by fetal tobacco smoke exposure on the development of subsequent infantile eczema

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000027834
Enrollment
500
Registered
2017-06-20
Start date
2018-10-10
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eczema

Interventions

None listed

Sponsors

Departments of Pediatrics Juntendo University, Faculty of Medicine 3-1-3 Hongo, Bunkyo-ku TOKYO, 113-0033, JAPAN TEL +81-3-3813-3111 FAX +81-3-5800-1580
Lead Sponsor
Department of Allergy and Clinical Immunology, National Research Institute for Child Health and Development, Tokyo
Collaborator
Dr. Kenji Matsumoto The University of Western Australia, Faculty of Health and Medical Sciences, Perth Children&#39
Collaborator
s Hospital, Telethon Kids Institute, Australia
Collaborator
Professor. Susan Prescott Perth Children&#39
Collaborator
s Hospital, Telethon Kids Institute. Research psychologist with the ORIGINS Project, Australia
Collaborator
Dr. Lisa Gibson Department of Allergy, Tokyo Metropolitan Children&#39
Collaborator
s Medical Center, Tokyo
Collaborator
Dr. Masami Narita Department of Epidemiology and Preventive Medicine, Graduate School of Medicine, Ehime University, Ehime
Collaborator
Dr. Keiko Tanaka Okayama Saiseikai General Hospital Department of Pediatrics, Section Head, Dr. Testuro Kitamura
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: *Pregnant women (>= 28 gestation weeks) *Pregnant mother and father with allergic diseases *Pregnant mother and father without allergic diseases

Exclusion criteria

Exclusion criteria: *Pregnant mother with using medication *Pregnant mother and father with chronic diseases, expect allergic diseases *Pregnant mother who do not want avoid smoking *Infants who born by cesarean section *Premature infants *Infants with with chronic diseases, expect allergic diseases *Invidivuals with using supplements including vitamine *Individuales with judgement of ineligible by a responsible researcher

Design outcomes

Primary

MeasureTime frame
Exploration of transgenerational hair-related miRNA

Secondary

MeasureTime frame
kinds of hair-related miRNA

Countries

Japan,North America,Australia

Contacts

Public ContactMiwa Shinohara

Juntendo University, Faculty of Medicine Department of Pediatrics

mi-shinohara@juntendo.ac.jp03-3813-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026