Effect of brimonidine on the ocular circulation

Effect of brimonidine on the ocular circulation - Effect of brimonidine on the ocular circulation

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000027826

Enrollment

Registered

2017-07-01

Start date

2017-06-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Interventions

Measurement of the retinal blood flow by Doppler optical coherence tomography (DOCT) (Before start brimonidine and 3 months after start brimonidine)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Subjects able to understand the written informed consent and willing to participate evidenced by signing the informed consent 2)Glaucomatous changes in the fundus 3)Abnormal glaucomatous visual field according to the Anderson-Patella classification in the Swedish interactive threshold algorithm (SITA)-standard strategy of the 30-2 program of the Humphrey field analyzer (HFA) 4)Subjects administered with additional brimonidine

Exclusion criteria

Exclusion criteria: 1)Cataract and previous cataract surgery 2)High ametropia 3)Subjects with cardiovascular disease such as untreated hypertension and diabetes mellitus 4)Previous ocular surgery 5)Difficulty for perform examination

Design outcomes

Primary

Measure	Time frame
Retinal blood flow	—

Countries

Japan

Contacts

Public ContactTakayuki Kamiya

Asahikawa Medical University Ophthalmology

t-kamiya@asahikawa-med.ac.jp0166-68-2543

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026