Healthy adults
Conditions
Interventions
Ingestion of yogurt drink containing lactic acid bacteria LH strain for 12 consecutive weeks
Ingestion of yogurt drink without lactic acid bacteria LH strain for 12 consecutive weeks
Sponsors
TTC Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1)Subjects aged from 20 to 64 years old (2)Subjects with discomfort of eyes and nose(sneeze,runny nose, nasal) (3)Subjects positive for specific IgE(RAST)against house dust or mite. (4)Subjects who are judged as healthy adult for the study by the investigator
Exclusion criteria
Exclusion criteria: (1)Subjects who routinely take foods or medicines containing of lactic acid bacteria. (2)Subjects who routinely take foods or medicines affecting the test result (3)Subjects who have history of regular visits of otorhinolaryngology or planned to clinic visits (4)Subjects who has received a diagnosis of seasonal allergic rhinitis (pollen allergy) (5)Subjects with acute rhinitis, sinusitis or hypertrophic rhinitis (6)Subjects with bronchial asthma (7)Subjects who are under treatment or have a history of serious disease(e.g., diabetes, liver disease, kidney disease, or heart disease) (8)Subjects who are under medication(e.g., hyposensitization)which may influence the outcome of the study (9)Subjects with allergies to the test food in the study (10)Subjects judged as unsuitable for the study by the investigator for laboratory evidence or cardiopulmonary function (11)Subjects who have a disease requiring regular medication or a history of serious diseases for which medication was required (12)Subjects who are judged as unsuitable for the study based on the results of clinical and physical examination on preliminary examination (13)Subjects who have participated in other clinical study within the last one month prior to the current study or are planned to participate in other clinical study after informed consent for the current study (14)Subjects who are planned to become pregnant after informed consent for the current study or are pregnant or lactating (15)Subjects who are judges as unsuitable for the study based on the results of lifestyle questionnaire (16)Subjects who are judged as unsuitable for the study by the investigator for other reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Questionnaire of discomfort of eyes and nose,Diary. Evaluate at points of 12-week and 4-week, 8-week | — |
Secondary
| Measure | Time frame |
|---|---|
| Specific IgE(RAST), IFN-Gamma, IL-13, Total IgE(RIST) | — |
Countries
Japan
Contacts
Public ContactChiharu Goto
TTC Co., Ltd. Clinical Research Planning Department
Outcome results
None listed