Finding out causes of breakthrough pain focused on circadian rhythm-related factors

Finding out causes of breakthrough pain focused on circadian rhythm-related factors - Finding out causes of breakthrough pain focused on circadian rhythm-related factors

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000027774

Enrollment

Registered

2017-06-16

Start date

2016-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cancer, Sleep disorder, Circadian rhythm disorder

Interventions

Subjects will be received following two interventions for three days. 1.Recording the time of breakthrough pain and the degree of pain (NRS). 2.Measuring circadian rhythm related factors (actigraph,

s hospital sleep questionnaire, urine 6-sulfatoxymelatonin and so on). In addition, assessment anxiety and depression by HAD at getting informed consent.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Cancer patients without changing opioid medication for more than three days.

Exclusion criteria

Exclusion criteria: Cancer patients with heavy dementia, <= PS2, on anticancer drug medicaton.

Design outcomes

Primary

Measure	Time frame
The relationship between breakthrough pain and circadian rhythm related factors	—

Countries

Japan

Contacts

Public ContactKazuyuki NIki

Osaka University/Ashiya Municipal Hospital Graduate School of Pharmaceutical Sciences/Department of Pharmacy

k-niki@phs.osaka-u.ac.jp06-6879-8250

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026