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Effect of Autogenous Cortical Bone Particulate in Conjunction With Fibroblast Growth Factor in the Treatment of Periodontal Intraosseous Defects

Effect of Autogenous Cortical Bone Particulate in Conjunction With Fibroblast Growth Factor in the Treatment of Periodontal Intraosseous Defects - Autogenous Bone Graft and FGF Versus FGF Versus ABG in Intraosseous Defects

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000027743
Enrollment
60
Registered
2017-06-13
Start date
2017-06-13
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontal Desease

Interventions

After local anesthesia, buccal and lingual sulcular incisions were made and mucoperiosteal flaps were elevated. Flap design in the interdental area consisted of one of the following alternatives.1) s
distance from the contact point or area to the bone crest, as radiographically assessed
apico coronal width of interdental keratinized tissue in the area of intraosseous defect. Vertical incisions were placed mesial or distal to the treated defect, if they were considered necessary for

Sponsors

kanagawa dental university yokohama clinic
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: kanagawa dental university yokohama clinic that meets the following criteria out of 20 years of age diagnosed as chronic periodontitis or aggressive periodontitis A)patient with periodontal pocket of more than 6mm in the retest after basic periodontal treatment and 4mm or more in the bone defect in the intra oral X ray examination B)patient without diabetes, smoking, heart disease, pregnancy, or oral malignancy C)prior to periodontal surgery plaque control and bleeding on probing is less than 20%

Exclusion criteria

Exclusion criteria: D)third molar teeth, degree of mobility 3, furcation involvement lesion only, incompatible repair and prosthesis, inappropriate root canal treatment teeth. patients who judged inappropriate by the responsible doctor.

Design outcomes

Primary

MeasureTime frame
perform clinical attachment level (position of bottom of pocket from cement-enamel junction) at 3 months, 6 months, 12 months after surgery with preoperative baseline

Secondary

MeasureTime frame
Gingival Index(GI), Plaque Index(PI), Bleeding on probing(BOP), Probing Pocket Depth(PPD), gingival Recession(REC are performed at before surgery, 3 months, 6 months, 12 months after surgery. X-ray examination is carried out at pre-operation, 3 months, 6 months, 12 months after surgery with simple X-ray standard photography using silicon putty.

Countries

Japan

Contacts

Public Contactyohei kamata

kanagawa dental university yokohama clinic department of highly advanced stomatology

kamata@kdu.ac.jp045-313-0007

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026