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The investigation for the time course of bronchoconstriction triggered cough reaction induced by Methacholine using Astograph method

The investigation for the time course of bronchoconstriction triggered cough reaction induced by Methacholine using Astograph method - The time course of bronchoconstriction triggered cough reaction induced by Methacholine

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000027735
Enrollment
15
Registered
2017-06-13
Start date
2017-06-14
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cough variant asthma

Interventions

day1 The measurement of cough response to bronchoconstriction induced by Methacholine using Astograph method day2 The measurement of cough response to bronchoconstriction induced by Methacholine usi

Sponsors

Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Male and female healthy subjects >= 20 years of age are eligible for inclusion. No symptom and history of respiratory disease, cardiovascular disease, gastrointestinal disease, hepatobiliar-pancreatic disease, endocrine and metabolic disease, hematological and malignant disease, renal disease, neuromuscular disease, collagen disease, autoimmune disease, psychosomatic and mental disorder, chronic infectious disease, obstetric and gynecological disease, urological disease, cerebral nervous disease.

Exclusion criteria

Exclusion criteria: Key exclusion criteria were: tachyarrhythmia, heart failure; women of childbearing potential or of breast-feeding; mental disorder or psychiatric symptom; several medical conditions prohibiting partitipation.

Design outcomes

Primary

MeasureTime frame
The investigation for the time course of bronchoconstriction triggered cough reaction induced by Methacholine

Countries

Japan

Contacts

Public ContactJohsuke Hara

Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University Department of Respiratory Medicine

hara0728@gmail.com076-265-2000

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026