Molecular genetic elucidation of pharmacokinetics of propofol

Molecular genetic elucidation of pharmacokinetics of propofol - Relationship between propofol and genes

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000027630

Enrollment

100

Registered

2017-06-04

Start date

2017-05-29

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Relationship between propofol and genes

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ASA1-2 elective surgery

Exclusion criteria

Exclusion criteria: weight<70%, >130% disease or injury affecting the central nervous system recent use of psychoactive or analgesic medication

Design outcomes

Primary

Measure	Time frame
Identification of candidate SNPs(UGT1A9,CYP2B6,CYP2C9 affecting pharmacokinetics of propofol	—

Secondary

Measure	Time frame
Validation of candidate SNPs	—

Countries

Japan

Contacts

Public ContactAkihiro Kanaya

Tohoku University School of Medicine Department of Anesthesiology and Perioperative Medicine

a-kanaya@med.tohoku.ac.jp022-717-7321

Outcome results