New measurement method of glucagon in patients with heart disease

New measurement method of glucagon in patients with heart disease - New glass study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000027624

Enrollment

Registered

2017-06-06

Start date

2017-06-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with heart diseaes and non heart disease who had never diabetes

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with or without heart disease who had never diabetes

Exclusion criteria

Exclusion criteria: 1.over HbA1c 8.0 percent 2.Uncontrol hemodynamics stage in heart disase 3.No informed consent

Design outcomes

Primary

Measure	Time frame
Difference value of AUC (area under the curve) glucagon in patient with or without heart disease(Sandwich ELISA).75gOGTT(oral glucose tolerance test) during 4h method.	—

Secondary

Measure	Time frame
1.Each 0 to 4h, difference value of glucagon (Sandwitc ELISA) in patients with or without heart disease. 2.Each 0 to 4h, difference value of glucagon (RIA) in patients with or without heart disease. 3.Difference value of AUC glucagon (RIA and Sandwich ELISA) in patients with heart disease. 4.Difference value of AUC glucagon (Sandwitc ELISA and RIA) in patients without heart disease. 5.Each 0 to 4h, difference value of glucagon (Sandwitc ELISA and RIA) in patients with heart disease. 6.Each 0 to 4h, difference value of glucagon (Sandwitc ELISA and RIA) in patients without heart disease. 7.Relation between each 0 to 4h and AUC value of glucagon (Sandwitc ELISA and RIA) in patients and cardiac functions(EF,E/A,E/E',rest and exercie heart rate, anaerobic threhsold, peak VO2, O2 pulse, PETCO2, minimum VE/VCO2, VE vs VCO2 slope)	—

Measure

Time frame

1.Each 0 to 4h, difference value of glucagon (Sandwitc ELISA) in patients with or without heart disease. 2.Each 0 to 4h, difference value of glucagon (RIA) in patients with or without heart disease. 3.Difference value of AUC glucagon (RIA and Sandwich ELISA) in patients with heart disease. 4.Difference value of AUC glucagon (Sandwitc ELISA and RIA) in patients without heart disease. 5.Each 0 to 4h, difference value of glucagon (Sandwitc ELISA and RIA) in patients with heart disease. 6.Each 0 to 4h, difference value of glucagon (Sandwitc ELISA and RIA) in patients without heart disease. 7.Relation between each 0 to 4h and AUC value of glucagon (Sandwitc ELISA and RIA) in patients and cardiac functions(EF,E/A,E/E',rest and exercie heart rate, anaerobic threhsold, peak VO2, O2 pulse, PETCO2, minimum VE/VCO2, VE vs VCO2 slope)

—

Countries

Japan

Contacts

Public ContactMakoto Murata

Gunma Prefectual Cardiovascular Center Deperatment of Cardiology

yarukimanmann2000@yahoo.co.jp027-269-7455

Outcome results