Radiotherapy for glioblastoma: Dose escalation trial of IMRT after hyperbaric oxygen therapy

Radiotherapy for glioblastoma: Dose escalation trial of IMRT after hyperbaric oxygen therapy - Dose escalation trial of IMRT after hyperbaric oxygen for glioblastoma

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000027623

Enrollment

Registered

2017-06-03

Start date

2017-05-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glioblastoma

Interventions

The IMRT boost doses were then continuously delivered to the GTV plus 5 mm and the surrounding edema. Each IMRT boost session was performed immediately after HBO to achieve radiosensitization. Group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Pathological diagnosis of glioblastoma KPS>30

Exclusion criteria

Exclusion criteria: Without brain stem invasion. Gliomatosis cerebri

Design outcomes

Primary

Measure	Time frame
Cranial nerve disorder at one, 3, 5, and 7 weeks after the treatments. CT and MR images, each 3 month after the treatments.	—

Countries

Japan

Contacts

Public ContactTakayuki Ohguri

University of Occupational and Environmental Health Radiology

ogurieye@med.uoeh-u.ac.jp093-603-1611

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026