Hematopoietic stem cell transplant recipients
Conditions
Interventions
Start RS-rich diet and dietary supplement at the initiation of conditioning regimen, continuing through day +28.
Sponsors
Tokyo metropolitan Cancer and Infectious diseases Center, Komagome hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) HSCT recipients. 2) Ability to understand and the willingness to sign a written informed consent.
Exclusion criteria
Exclusion criteria: 1) Subjects who are at risk of aspiration. 2) Subjects who are prohibited from eating for any reason. 3) Subject who have an allergy to provided prebiotics. 4) Subjects who are diagnosed with ileus. 5) Any physical or psychological condition that, in the opinion of the investigator, would pose unacceptable risk to the patient or raise concern that the patient would not comply with protocol procedures.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence and duration of severe (grade 3 or more) mucositis | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Cumulative incidence of acute GVHD 2) Duration of total parenteral nutrition | — |
Countries
Japan
Contacts
Public ContactKazuhiko Kakihana
Tokyo metropolitan Cancer and Infectious diseases Center, Komagome hospital Hematology division
Outcome results
None listed