obstructive sleep apnea syndrome
Conditions
Interventions
Self oral myofunctional theraphy is performed three times a day for 6 months. Patients are also educated to be conscious of nasal breathing and write down the daily report.
Sponsors
Tokyo Women's Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. out patients of Division of Comprehensive Sleep Medicine in Tokyo Women's Medical University Hospital 2. Participant is diagnosed moderate or severe obstructive sleep apnea syndrome , who are treated using continuous positive airway pressure(CPAP) or oral appliance(OA) for more than 6 months. 3. Participant has no extreme body weight change from first diagnosed time.
Exclusion criteria
Exclusion criteria: 1.mild obstructive sleep apnea syndrome 2.Participant has severe nasal obstruction. 3.obesity (BMI over 30) 4.Participant is recognized to be inadequate by principal investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| changes of apnea hypopnea index(AHI) between before and 6 month after training | — |
Secondary
| Measure | Time frame |
|---|---|
| arousal index, minimum oxygen saturation,mean oxygen saturation, oxygen desaturation index,sleep stages,snore index, Epworth sleepiness scale,Pittsburgh sleep quality index, frequency of nocturia, red blood cell,hemoglobin,white blood cell,platelet,total protein, albumin, AST,ALT, LDH, creatinine,LDL cholesterol,HDL cholesterol,triglyceride, HbA1C, blood suger,high sensitive C reactive protein,tongue pressure,circumference of abdomen and neck Change of these factors above between before and 6 month after training | — |
Countries
Japan
Contacts
Public ContactMayumi Suzuki
Tokyo Women's Medical University Department of Cardiology(Division of Comprehensive Sleep Medicine)
Outcome results
None listed