Phase one/ two clinical trial of boron neutro capture therapy for head and neck malignancies

Phase one/ two clinical trial of boron neutro capture therapy for head and neck malignancies - Clinical trial of BNCT for head and neck malignancies

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000027543

Enrollment

Registered

2017-08-01

Start date

2017-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Head and Neck cancers

Interventions

BPA is administrated as boron carrier and research reactor is utilized as neutron source.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.With head and neck tumors that have relapsed after conventional therapies 2.Without distant metastases 3.PS is less than 2 4.Tumor to Normal tissue boron ratio is more than 2.5 using 18F-BPA-PET 5.Consent to perform BNCT 6.With the approval of the Medical Ethics Committee

Exclusion criteria

Exclusion criteria: 1.with severe complications 2.medically or socially unacceptable patients 3.with pace maker

Design outcomes

Primary

Measure	Time frame
tumor response	—

Countries

Japan

Contacts

Public ContactKawanishi

Kawasaki Medical School Division of Research Sopport

kenkyu-idai@med.kawasaki-m.ac.jp086-462-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026