Swallowing ability and respiratory condition during intravenous sedation

Swallowing ability and respiratory condition during intravenous sedation - Swallowing ability and respiratory condition during intravenous sedation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000027517

Enrollment

Registered

2017-05-28

Start date

2017-05-28

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy adult volunteer

Interventions

Intravenous adminisitration of propofol using TCI pump. (copntrol, 0.5 microgram/ml, 1.0 microgram/ml, 1.5 microgram/ml) Target concentration is increased after the swallowing test in each concentrat

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: healthy adult

Exclusion criteria

Exclusion criteria: 1. History of velopharyngeal insufficiency; palatal, pharyngeal or laryngeal surgery; speech or swallowing impairment; and trismus. 2. Contraindication of propofol (1) History of allergic reaction to propofol, egg yolk or soybean (2) Pregnancy or breast-feeding

Design outcomes

Primary

Measure	Time frame
The volume of residualwater during swallowing test	—

Secondary

Measure	Time frame
Electromyogram during swallowing test, resipiratory rate, partial pressure of end tidal carbon dioxide	—

Countries

Japan

Contacts

Public ContactHiroshi Hanamoto

Osaka University Graduate School of Dentistry Department of Dental Anesthesiology

hanamoto@dent.osaka-u.ac.jp+81-6-6879-2972

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026