Evaluation for efficacy of liver function by ingestion of supplement containing plant derived extractive

Evaluation for efficacy of liver function by ingestion of supplement containing plant derived extractive - Evaluation for efficacy of liver function by ingestion of supplement containing plant derived extractive

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000027495

Enrollment

Registered

2017-05-26

Start date

2017-05-27

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy subjects

Interventions

Intake of supplement containing plant derived extractive for 12 consecutive weeks (4 capsules, 1 time a day) Intake of placebo for 12 consecutive weeks (4 capsules, 1 time a day)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Healthy males and females aged 20-64 years old 2.Subjects with BMI greater than 22.0 and less than 30 kg/m^2 3.Subjects who ALT levels were top 40 out of the participants applying to the criteria (both ALT and AST less than 50 U/L) 4.Subjects who has normal or borderline liver function judged by clinical investigator

Exclusion criteria

Exclusion criteria: 1.Subjects who constantly use health food richly containing involvement ingredient 2.Subjects who constantly use supplements or drug affecting the liver function 3.Subjects with chronic illness or medication 4.Subjects who has serious illness such as diabetes, liver disease, kidney disease, heart disease 5.Subjects who are in danger of allergy to the study 6.Subjects who have participated in other clinical study within the last one month or have plan to participate other clinical studies 7.Subjects who are judged as unsuitable for the study from clinical measurements for preliminary tests and measurements 8.Subjects who are positive for HCV antibody or HbsAg 9.Subjects who intend to become pregnant or lactating 10.Subjects who are judged as unsuitable for the study based on the results of lifestyle questionnaire 11.Subjects who are judged as ineligible by clinical investigator

Design outcomes

Primary

Measure	Time frame
Biomarkers of liver function (ALT and AST) before and 4, 8, 12 weeks after the intervention with the test food	—

Secondary

Measure	Time frame
Biomarkers of liver function (gamma-GT and ALP), POMS2, LPO, Physical, Hematologic, Blood biochemical, Urinalysis, and Psychological values before and 4, 8, 12 weeks after the intervention with the test food	—

Countries

Japan

Contacts

Public ContactKotoha Isobe

TTC Co., Ltd. Clinical Research Planning Department

k.isobe@ttc-tokyo.co.jp03-5459-5329

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026