A multicenter, prospective, validation study for mew sepsis definition in intensive care unit

Conditions

Sepsis

Ryo Yamamoto, Seitaro Fujishima, Kazuma Yamakawa, Toshikazu Abe, Hiroshi Ogura et al. (8 authors)

BMJ Open Respiratory Research2023-12-016 citations

10.1136/bmjresp-2023-001968

Epidemiology of sepsis and septic shock in intensive care units between sepsis-2 and sepsis-3 populations: sepsis prognostication in intensive care unit and emergency room (SPICE-ICU).

Abe T, Yamakawa K, Ogura H, Kushimoto S, Saitoh D, Fujishima S, Otomo Y, Kotani J, Umemura Y, Sakamoto Y, Sasaki J, Shiino Y, Takeyama N, Tarui T, Shiraishi SI, Tsuruta R, Nakada TA, Hifumi T, Hagiwara A, Ueyama M, Yamashita N, Masuno T, Ikeda H, Komori A, Iriyama H, Gando S, JAAM SPICE Study Group.

2020-06-3039 citations

10.1186/s40560-020-00465-0

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: All patients who presented in ICU with a clinical suspicion of infection diagnosed by treating emergency physicians or intensivists, followed by the orders to explore origins or organisms of the infection by cultures or radiological images, or beginning of the treatments for infection.

Exclusion criteria

Exclusion criteria: Patients with recurrent infection. Patients who accepted DNAR orders.

Design outcomes

Primary

Measure	Time frame
Hospital mortality (survival, death)	—

Secondary

Measure	Time frame
1. 28-day mortality 2. Validation of SIRS, qSOFA, and SOFA for characteristics of sepsis diagnosis 3.Ventilator free day, ICU free days 4.Validation of SOFA score	—

Countries

Japan

Contacts

Public Contactshuta FUKUDA

Japanese Association for Acute Medicine Head office

jaam-6@bz04.plala.or.jp+81-3-5840-9870

Outcome results