Effect of lactic acid bacteria beverage on liver function

Effect of lactic acid bacteria beverage on liver function - Effect of lactic acid bacteria beverage on liver function

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000027440

Enrollment

Registered

2017-05-23

Start date

2017-06-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild liver disease

Interventions

Subjects drink 120 mL/day of lactic acid bacteria beverage containing live Lactobacillus plantarum SN13T for 16 weeks. Subjects drink 120 mL/day of lactic acid bacteria beverage containing dead Lacto

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 40<AST<100 U/L, 40<ALT<100 U/L, or 70<r-GTP<210 U/L for male; 30<r-GTP<90 U/L for female

Exclusion criteria

Exclusion criteria: 1) Diagnosis of virus hepatitis, autoimmune hepatitis, or cirrhosis of liver 2) Taking drugs for chronic disease or continuously taking anti-flatulent, antibiotics, or purgative drug that possibly affects the intestinal flora 3) Allergy to milk 4) Participation in any clinical trial within 90 days of the commencement of the trial 5) In pregnancy or nursing a child 6) Judged as ineligible by clinical investigators

Design outcomes

Primary

Measure	Time frame
16-week changes in ALT, AST, and r-GTP	—

Secondary

Measure	Time frame
16-week changes in TC, HDL-C, TG, FBS, insulin, HOMA-IR, leptin, adiponectin, TNF-a, intestinal flora, and defecation frequency	—

Countries

Japan

Contacts

Public ContactFumiko Higashikawa

Hiroshima University, Institute of Biomedical & Health Sciences Project Research Center for Clinical Trial and Preventive Medicine

fumiko@hiroshima-u.ac.jp082-257-1533

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026