None
Conditions
Interventions
Ingestion of Wasabi-sulfinyl(R) containing foods for 8 weeks
Ingestion of placebo for 8 weeks
Sponsors
TTC Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Men and women aged from 45 to 69 2) Subjects with self-awareness of forgetfulness 3) Subjects with inferior scores of cognitive function tests
Exclusion criteria
Exclusion criteria: 1) Subjects who are difficult to discriminate color 2) Subjects with bad eyesight, or are diagnosed with amblyopia or blindness 3) Subjects with bad hearing, or are diagnosed with hearing loss or permanent hearing loss 4) Subjects who get a score of 20 or less on the Revised HDS-R 5) Subjects with history of cranial nerve disease 6) Subjects who have depressive symptoms, or who have been diagnosed as depressive disorder 7) Subjects who are under hormone treatment or are diagnosed with menopause 8) Subjects who have some irregular schedules during the study, due to night work or something 9) Subjects who drink much alcohol 10) Subjects who smoke, or quit smoking within one year before pre-inspection 11) Subjects who have done the same cognitive function test within one year before pre-inspection 12) Subjects who are under treatment of cognitive functions, or are prescribed with medicine for them 13) Subjects who continuously take medicine, health foods, Food for Specified Health Uses or Foods with Function Claims including substance related to cognitive functions 14) Subjects who was given or donated 200 ml or 400 ml whole blood within three months before pre-inspection 15) Subjects who participated in other study within one month before pre-inspection, or are going to participate in other study during the study 16) Subjects who have a disease which needs regular medication, or have a history of the disease 17) Subjects who are judged as unsuitable for the study by investigator because of clinical test, anthropometric test and physical examination in pre-inspection 18) Subjects who are in danger of allergy to the study 19) Subjects who are pregnant or lactating, or plan to become pregnant or lactate during the study 20) Subjects who are judged as unsuitable for the study because of lifestyle questionnaire 21) Subjects who are judged as unsuitable for the study by investigator for other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rey Auditory Verbal Learning Test, Paced Auditory Serial Addition Test | — |
Secondary
| Measure | Time frame |
|---|---|
| Tapping Span , Memory of the graphic, Purdue Pegboard Test, Stroop test, Brain-derived neurotrophic factor, questionnaires | — |
Countries
Japan
Contacts
Public ContactKotoha Isobe
TTC Co., Ltd. Clinical Research Planning Department
Outcome results
None listed