The construction of an effective program for those with mild cognitive impairment or mild dementia: the direct and spreading effect of a short-term intensive training

The construction of an effective program for those with mild cognitive impairment or mild dementia: the direct and spreading effect of a short-term intensive training - An Intervention Study of Rehabilitation Program Using Physical and Cognitive Rec-Xercise for Mild Cognitive Impairment and mild demantia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000027395

Enrollment

256

Registered

2017-05-18

Start date

2014-09-15

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild cognitive impairment Mild dementia

Interventions

The cognitive Rec-Xercise group (A): subjects receive the session once per week up to 12 times. During the intervention period, the subjects were required to do everyday home-work. After the interve

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: MMSE total score is above 20

Exclusion criteria

Exclusion criteria: 1) Parkinson's disease, Huntington's disease, normal pressure hydrocephalus, brain tumor, progressive supranuclear palsy, corticobasal degeneration, epilepsy, subdural hematoma, multiple sclerosis, traumatic brain injury with cognitive impairment 2) Cerebrovascular disease with responsible lesions of cognitive impairment on MRI 3) Schizophrenia, major depressive or bipolar episode during the past year, alcohol or drug addiction for the past two years, vitamin B12 deficiency, folate deficiency, syphilis, thyroid dysfunction 4) Apparent mental retardation or suspicious mental retardation 5) The case not qualified for the study by the principal investigator

Design outcomes

Primary

Measure	Time frame
When: before and right after the intervention, 3, 6, 12, 18, 24, 36, 48, 60, 72, 84, 96, 108 and 120 months after the intervention Outcome measure: MMSE total score	—

Secondary

Measure	Time frame
MMSE total score, MoCA total score, RBMT, RCPM, TMTA & TMTB POMS TMIG-index of competence, JST SF36 6MD, TUG, Grip strength MRI Nutrition Laboratory data	—

Countries

Japan

Contacts

Public ContactYoshie Kawaji

Tokyo Metropolitan Geriatric Hospital Clinical Psychology

yoshie_kawaji@tmghig.jp0339641141

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Sep 19, 2026