Healthy volunteers
Conditions
Interventions
Test food with plants extract (single ingestion) - washout period - placebo food without plants extract (single ingestion)
Placebo food without plants extract (single ingestion) - washout period - tes
Sponsors
Lotte Co., Ltd.
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: (1) Subjects who are sensitive to cold (2) Females from 20 to 49 years of age (3) Subjects giving written informed consent
Exclusion criteria
Exclusion criteria: (1) Individuals who are under treatment or have a history of Cardiovascular disease (including cardiac infarct, arrhythmia, high-blood pressure, ischemic cardiac disease, aneurysm of aorta, dissection of the aorta, diabetes, renal failure, low-blood pressure etc. ) (2) Individuals who are currently suffering from some disease and undergoing drug treatment (3) Individuals taking drugs (including aspirin and warfarin etc.), health foods and foods with function claims (including hesperidin and ginger etc.) in common use, which influence blood flow (4) Shift worker at midnight and irregular time zones (5) Individuals presenting known food allergy (6) Individuals who are pregnant or breast-feeding, or have the will of pregnancy during the study period (7) Individuals who are judged as unsuitable for the study by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin surface temperature of fingertip following the exposure to cold water stress. Blood flow of fingertip following the exposure to cold water stress. | — |
Secondary
| Measure | Time frame |
|---|---|
| Feeling questionnaire. | — |
Countries
Japan
Contacts
Public ContactKeishiro Yoshida
Lotte Co., Ltd. Central Laboratory, Food material development section
Outcome results
None listed