Low dose of lactulose for intestinal function. Randomized double-blind, placebo-controlled crossover study

Low dose of lactulose for intestinal function. Randomized double-blind, placebo-controlled crossover study - Low dose of lactulose for intestinal function

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000027305

Enrollment

Registered

2017-05-15

Start date

2017-05-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intake of lactulose 2g/day for 2weeks Intake of placebo for 2weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Subjects with feces frequency 2-4 times / week

Exclusion criteria

Exclusion criteria: 1) Subjects with severe hepatic, renal, heart, gastrointestinal, cerebrovascular, endocrine, metabolic or infection diseases. 2) Subjects with the history of gastrointestinal resection. 3) Subjects with gastrointestinal dysfunction such as irritable bowel syndrome or inflammatory bowel disease. 4) Subjects who use medicines or supplements that may influence feces frequency; e.g. antibiotics, probiotics, laxatives, antidiarrheals, fibers. 5) Subjects with milk allergy. 6) Subjects with lactose intolerance 7) Subjects who participate another study. 8) Subjects who are judged inappropriate for the study by the investigator or the physician.

Design outcomes

Primary

Measure	Time frame
Feces frequency	—

Secondary

Measure	Time frame
Defecation number of days, Feces hardness, Volume of feces	—

Countries

Japan

Contacts

Public ContactHisakazu Iino

Showa Women's University Graduate School, Science for Living System

iino@swu.ac.jp03-3411-4828

Outcome results