Skip to content

Carbon-ion radiotherapy for solitary lymph node recurrence: a retrospective multicenter observational study

Carbon-ion radiotherapy for solitary lymph node recurrence: a retrospective multicenter observational study - Carbon-ion radiotherapy for solitary lymph node recurrence: a retrospective multicenter observational study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000027300
Enrollment
310
Registered
2017-05-10
Start date
2017-07-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Solitary lymph node recurrence

Interventions

None listed

Sponsors

Hospital of the National Institute of Radiological Sciences, National Institutes for Quantum and Radiological Sciences and Technology
Lead Sponsor
Gunma University Heavy Ion Medical Center Hyogo Ion Beam Medical Center Ion Beam Therapy Center, SAGA HIMAT Foundation
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Among patients who underwent carbon-ion radiotherapy in participating facilities between December 1996 and December 2015, patients who meet the following eligible criteria. 1) Patients who had diagnosed histologically or clinically as solitary lymph node recurrence. 2) Recurrence in single one lymph node region. 3) Lymph node recurrence could be included in an irradiation field. 4) There are no other recurrent lesions except the lymph node recurrence. 5) Tumor diameter could be measured by CT or MRI. 6) The age at starting of the carbon-ion radiotherapy was 20 years old and older. 7) Carbon-ion radiotherapy was administered to the lymph node recurrence.

Exclusion criteria

Exclusion criteria: 1)Tumor invasion to GI tract. 2)Severe or active nfections in the irradiated area. 3)Severe concomitant illness.

Design outcomes

Primary

MeasureTime frame
2-year local control, course-specfic survival, and overall survival rates. Incidence of Grade 2 or worse late toxicities

Countries

Japan

Contacts

Public ContactOkonogi Okonogi

National Institutes for Quantum and Radiological Sciences and Technology Hospital of the National Institute of Radiological Sciences

okonogi.noriyuki@qst.go.jp043-206-3306

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026