Analysis of Hemostasisarrest of Bleeding for Patients with Direct Oral Anti-Coagulant after Tooth Extraction Based on the Duration of DOAC Administration and Serum Concentration

Analysis of Hemostasisarrest of Bleeding for Patients with Direct Oral Anti-Coagulant after Tooth Extraction Based on the Duration of DOAC Administration and Serum Concentration - Analysis of Hemostasisarrest of Bleeding for Patients with Direct Oral Anti-Coagulant after Tooth Extraction

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000027293

Enrollment

Registered

2017-08-24

Start date

2017-07-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

over 65 years-old prevalence elderly

Interventions

Control of duration from the administration of DOAC to the start of extraction

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.The patients who have medical examination in Tokyo Medical and Dental University of special care 1 department 2. The patients who are electively undergo teeth extraction 3. The patients with ASA PS 2-3 4. The patients who can subscribe to informed consent

Exclusion criteria

Exclusion criteria: The patients with two types of anticoagulants

Design outcomes

Primary

Measure	Time frame
Analysis of bleeding We will evaluate 0-4 grades as follows. 0:No bleeding is detected from the site of tooth extraction before suture. 1:No bleeding is detected from the site of tooth extraction after suture. 2:No bleeding is detected from the site of tooth extraction after 5 min pressure homostasis after suture. 3:Bleeding is detected from the site of tooth extraction after 5 min pressure homostasis.	—

Measure

Time frame

Analysis of bleeding We will evaluate 0-4 grades as follows. 0:No bleeding is detected from the site of tooth extraction before suture. 1:No bleeding is detected from the site of tooth extraction after suture. 2:No bleeding is detected from the site of tooth extraction after 5 min pressure homostasis after suture. 3:Bleeding is detected from the site of tooth extraction after 5 min pressure homostasis.

—

Secondary

Measure	Time frame
Serum concentration of DOAC, PT, APTT	—

Countries

Japan

Contacts

Public ContactKazumasa Kubota

Tokyo Medical and Dental University Gerodontology and Oral Rehabilitation, Department of Gerontology and Gerodontology, Graduate Schoo

kuboanph@tmd.ac.jp03-5803-4560

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026