Healthy adults
Conditions
Interventions
Intake fermented milk containing Bifidobacterium for 8 weeks
Intake placebo for 8 weeks
Sponsors
KSO Corporation
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Healthy men and women aged from 20 to 65 years old. 2)Subjects whose stool frequency is about 3 to 5 times a week. 3)Subjects who have low relative abundance of bifidobacterium in feces 4)Subjects who have low diversity of microbiota in feces. 5)Subjects who understand details of the study and provides informed consent by documents.
Exclusion criteria
Exclusion criteria: 1)Subjects who regularly use intestinal drugs or laxatives. 2)Subjects who take drugs which affect gut microbiota such as antibiotics. 3)Subjects who have severe complication or serious diseases requiring an urgent treatment. 4)Subjects who have a chronic disease and use medicines constantly. 5)Subjects who have medical history of diseases or surgeries which affect digestion, absorption and defecation. 6)Subjects who repeat constipation and diarrhea such as irritable colitis. 7)Subjects who can't stop ingesting food containing lactic acid bacteria, bifidobacteria, oligosaccharide and viable bacteria. 8)Subjects who are under treatment for or have a history of drug addiction and/or alcoholism. 9)Subjects who are planning to become pregnant during the study or are pregnant or lactating. 10)Subjects who are planning to participate or already participating in other clinical studies. 11)Subjects who are judged as unsuitable for the study by the investigator for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gut microbiota | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Fecal properties (water content, pH) 2) Fecal organic acids 3) Uremic toxins | — |
Countries
Japan
Contacts
Public ContactEiji Yoshikawa
KSO Corporation Sales department
Outcome results
None listed