Severe alveolar bone atrophy
Conditions
Interventions
Non-cultured fresh isolated adipose cells
1x10^7 are mixed to TCP and rhBMP2 as implants.
Sponsors
Department of Regenerative Oral Surgely, Nagasaki University Graduate School of Biomediacal Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients who are partially or fully edentulous, and are required to treat by dental implants for prosthetic rehabilitation. 2. Patients who have insufficient bone height and/or width to place the dental implant 3. Patients who received the oral health care and maintain the good condition of Plaque Control. 4. The age of the patients: 20- to 70-years old
Exclusion criteria
Exclusion criteria: All patients are required to be nonsmokers. 2. Patients who have systemic disease, malignances, chronic infections, immune system abnormalities, septicemia, syphilis, HBV, HCV, HTLV-1, HIV, pregnancy, dementia. 3. Patients who have disorder of blood coagulation. 4. Patients who have hepatitis function disorders, metabolic bone disease or skeletal dysplasia. 5. Patients who needs the legal representative.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Safety (occurrence of adverse events) for two-years after transplantation | — |
Countries
Japan
Contacts
Public ContactYoshinori Sumita
Faculty of Dentistry, Nagasaki University Basic and Translational Research Center for Hard Tissue Disease
Outcome results
None listed