Effects of Isometric Handgrip Training on Blood Pressure in Patients with Heart Failure

Effects of Isometric Handgrip Training on Blood Pressure in Patients with Heart Failure - HANDGRIP-HF

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000027265

Enrollment

Registered

2017-05-08

Start date

2017-05-08

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart failure

Interventions

3 months of isometric handgrip exercise at 30% MVC(maximal voluntary contraction)for 2 minutes,4 times/day, 3 times/week. Contorol patients with no handgrip training

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Heart failure due to LV dysfunction 2. NYHA functional class I to III

Exclusion criteria

Exclusion criteria: 1. Systolic BP > 180mmHg 2. Additional antihypertensive medication 3. Severe valvular heart disease 4. ACS 5. Cardiogenic shock 6. Systolic BP after handgrip > 250mmHg 7. Pulmonary arterial hypertension and/or hypoxemia due to lung disease 8. Connective tissue disease 9. End-stage renal failure 10. Active inflammation 11. Short life expectancy due to malignancy

Design outcomes

Primary

Measure	Time frame
Ambulatory blood pressure after the 3 months of handgrip training	—

Secondary

Measure	Time frame
Office blood pressure Cardiovascular function 6 minutes walk distance Daily physical activity Muscle strength QOL Blood data	—

Countries

Japan

Contacts

Public ContactNaoki Fujimoto, MD, PhD

Mie University Graduate School of Medicine Department of Cardiology and Nephrology

naokifujimo@clin.medic.mie-u.ac.jp059-232-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026