Prediction of fluid responsiveness in patients undergoing thoracoscopic esophagectomy with prone position.

Prediction of fluid responsiveness in patients undergoing thoracoscopic esophagectomy with prone position. - Fluid responsiveness in patients undergoing thoracoscopic esophagectomy with prone position.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000027264

Enrollment

Registered

2017-05-10

Start date

2017-05-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer

Interventions

Implementation period:day (during surgery) Machine:Edwards Lifesciences EV1000 and FloTrac sensor When mean blood pressure decrease to 65 mmHg or less during thoracoscopic procedure with prone po

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Patients with esophageal cancer undergoing thoracoscopic esophagectomy with prone position. 2)Patient who are 20 years or older. 3)Patients with ASA physical status of 3 or less. 4)Patients capable of giving written informed consent for the participation in this study.

Exclusion criteria

Exclusion criteria: 1)Patients who are unable to have an operation with thoracoscopic approach. 2)Patients who cannot take prone position. 3)Patients who preoperatively have cardiac arrhythmia. 4)history of myocardial ischemia. 5)unstable angina pectoris. 6)history of pulmonary edema or congestive heart failure. 7)severe liver dysfunction (AST or ALT of 100 IU/L or greater). 8)severe renal dysfunction (Creatinine of 3 mg/dl or greater, or undergoing dialysis). 9)intracranial hemorrhage. 10)severe hypernatremia or severe hyperchloremia. 11)Pregnant women or women of childbearing potential. 12)Lactating women. 13)Inability to fully comprehend and/or perform study procedures in the investigator opinion.

Design outcomes

Primary

Measure	Time frame
ROC and AUC of PPV, SVV, PPV/SVV ratio, Heart rate, MAP and CVP to fluid responsiveness.	—

Secondary

Measure	Time frame
The changes in PPV, SVV, PPV/SVV ratio, CI, heart rate, MAP and CVP before and after the fluid bolus.	—

Countries

Japan

Contacts

Public ContactYukiko Hikasa

Okayama University Hospital Department of intensive Care

ichi_go_ichi_e_kokoro@yahoo.co.jp086-235-7778

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026