is EUS Guided Safe and effective in managing pancreatic cancer pain and with method is better ( Central VS Bilateral and what is the best time for intervention early or late salvage therapy ?
Conditions
Interventions
First group - central Endoscopic Ultrasound guided celiac nerve neurolysis in managing pain in patient with pancreatic cancer
second group - bilateral Endoscopic Ultrasound guided celiac nerve
Sponsors
cairo univesity , faculty of medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - age older than 18 years; - Severe abdominal or back pain due to confirmed pancreatic cancer (surgical biopsy or EUS-FNA) . - Presence of unrespectable pancreatic cancer (distant metastasis; the invasion of celiac trunk or superior mesentery artery) or intolerability to 3 surgery because of other systemic disorders. - Informed consent.
Exclusion criteria
Exclusion criteria: - Patients whose general condition cannot tolerate an endoscopic procedure. - Patient refusal of the procedure. - Acute abdominal complaint attributed to other causes. - Coagulopathy that makes the procedure risky.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| central endoscopic ultrasound guided versus bilateral celiac plexus neurolysis using absolute alcohol for pain control with pancreatic cancer which is better ? by assessing pain duration before the procedure, the dose and type of analgesic used, and visual analog scale pain score pre and post-treatment at day 7th , 14th and after two months. | — |
Secondary
| Measure | Time frame |
|---|---|
| The best Time of intervention early or salvage therapy Decreased requirement for analgesics | — |
Countries
Africa
Contacts
Public Contactadmin
faculty of medicine research affair
Outcome results
None listed