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Effects of hydroxyapatite agarose gel on the bone healing in the bony defect around the implant after immediate implant placement -retrospective study-

Effects of hydroxyapatite agarose gel on the bone healing in the bony defect around the implant after immediate implant placement -retrospective study- - Effects of hydroxyapatite agarose gel on the bone healing after implant placement

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000027172
Enrollment
50
Registered
2017-05-08
Start date
2016-10-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

missing teeth

Interventions

Hydroxyapatite agarose gel is a synthetic hybrid of organic and inorganic materials, and contains hemostatic material. Bone-like apatite could be formed on or in organic polymer hydrogel matrices via

Sponsors

Miyakonojo National Hospital Department of oral and Maxillofacial Surgery
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: good systemic and oral health, (2) radiographically >5-mm bone height defect between a reference point (implant-abutment interface) and the corresponding bone-to-implant contact point, (3) >2-mm gap between the implant and socket wall on baseline.

Exclusion criteria

Exclusion criteria: The exclusive criteria were use of potentially interfering medication (e.g., steroid therapy or bisphosphonates), alcohol or drug abuse noted in the patient's records of medical history, heavy smoking(more than 10 cigarettes/day), and uncontrolled diabetes.

Design outcomes

Primary

MeasureTime frame
Radiographic measurements of marginal bone loss were conducted via panoramic xray. The vertical distance between a reference point (implant-abutment interface) and the corresponding bone-to-implant contact point was measured (radiographic bone loss). The bone loss in millimeters detected radiographically was divided by the magnification factor to calculate actual bone loss. Bone level changes were calculated both medially and distally, based on the baseline and 3-year follow-up measurements. The deepest measurements of each implant at each time-point were calculated and recorded as proximal bone defect.

Secondary

MeasureTime frame
Peri-implant probing depth (PD) was determined at four sides of each implant, buccally, palatally, mesially, and distally. The deepest PD at the 3- year follow-up was recorded.

Countries

Japan

Contacts

Public Contactmasashi tabata

Miyakonojo National Hospital Oral and Maxillofacial Surgery

tabatam@mac.com0986-23-4111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026