Effect of screening for primary prevention of mortality and cardiovascular events using non-contrast T1-weighted magnetic resonance plaque imaging in high-risk patients estimated by risk factor categories for a Japanese urban population.

Effect of screening for primary prevention of mortality and cardiovascular events using non-contrast T1-weighted magnetic resonance plaque imaging in high-risk patients estimated by risk factor categories for a Japanese urban population. - Clinical significance of non-contrast T1-weighted plaque imaging for primary prevention of coronary artery disease

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000027101

Enrollment

660

Registered

2017-04-24

Start date

2017-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with primary prevention for coronary disease:hypertension, diabetes mellitus, dyslipidemia, stroke, aortic disease, atherosclerotic obliterans, or chronic kidney disease.

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Patients with high cardiac risk estimated by risk factor categories for a Japanese urban population Suita score(greater than 51 points). 2) Diabetic patients (more than 49 years old male or more than 54 years old female). 3) Patients with suspected of coronary artery disease who met criteria for intermediated coronary stenosis detected by CT angiography or invasive coronary angiography

Exclusion criteria

Exclusion criteria: 1) Internal metal 2) History of coronary artery disease (history of antianginal medication, CABG, or PCI) 3) Patients with severe stenosis detected by CTA. 4)refusal of informed consent

Design outcomes

Primary

Measure	Time frame
The primary outcome is a composite of all-cause mortality, carddiac mortality, stroke, nonfatal myocardial infarction, or ischemia proven unstable angina, stable effort angina, and silent myocardial ischemia, requiring coronary intervention.	—

Secondary

Measure	Time frame
Cardiac death. Composite of cardiovascular event of cardiac mortality, nonfatal myocardial infarction, ischemia proven unstable angina, stable effort angina, andsilent myocardial ischemia requiring coronary intervention. Prevalence of coronary HIP. Risk factor for coronary HIP. Analysis for cost-effectiveness.	—

Countries

Japan

Contacts

Public ContactTeruo Noguchi

National Cerebral and Cardiovascular Center Department of cardiovascular disease

tnoguchi@ncvc.go.jp06-6833-5012

Outcome results