Effects of intraocular pressure reduction in combined use with ripasudil and brimonidine, or pilocarpine in healthy adult volunteers.

Effects of intraocular pressure reduction in combined use with ripasudil and brimonidine, or pilocarpine in healthy adult volunteers. - Effects of IOP reduction in combined use with ripasudil and brimonidine, or pilocarpine.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000027065

Enrollment

Registered

2017-04-20

Start date

2016-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glaucoma

Interventions

ripasudil and brimonidine, or pilocarpine (one drop instillation) brimonidine (one drop instillation) ripasudil and brimonidine (one drop instillation) pilocarpine (one drop instillation) ripasudi

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: A person without ocular diseases.

Exclusion criteria

Exclusion criteria: Persons who are contraindicated for the test drugs. Persons who are allergic to ripasudil. Person who use contact lenses.

Design outcomes

Primary

Measure	Time frame
IOP reduction	—

Secondary

Measure	Time frame
Pupil diameter	—

Countries

Japan

Contacts

Public ContactTakashI Ono

Miyata Eye Hospital ophthalmology

ono@miyata-med.ne.jp0986-22-1441

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026