Alzheimer'
Conditions
Interventions
rTMS over the bil.DLPFC 10Hz 120%RMT 4sec stimulation 26sec inter train interval
Sponsors
Osaka University Graduate School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Alzheimer's dementia patient passed more than one year after the diagnosis 2. Patient with less than MMSE 25 points3. the cognitive function is insufficient 4. less than 20 years or older than 85 years old 5. The patient is provided in a document about the participation in this clinical study
Exclusion criteria
Exclusion criteria: 1.Patient with severe cognitive function 2.Severe aphasia, agnosia and aprxia 3.serious mental disorder 4.suicidal tendencies 5.the past of the epilepsy attack 6.the shrubbery model heart stimulation and assistance devices such as pacemakers 7.deep brain stimulation device 8.shrubbery metal on the head (except the titanium product) 9.Pregnant 10.Patient cannot answer a questionnaire 11.Patients received intervention in other clinical trials or a clinical trial within six months before the agreement acquisition 12.Patients are inappropriate as an object enrolled of this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ADAS-cog | — |
Secondary
| Measure | Time frame |
|---|---|
| MMSE, NPI, SC-BADA, Stroop test, functional MRI(Brain connectivity in resting state),EEG(LORRETA analysis) | — |
Countries
Japan
Contacts
Public ContactTomoo Mano
Osaka University Graduate School of Medicine Department of Neuromodulation and Neurosurgery
Outcome results
None listed