metastatic melanoma
Conditions
Interventions
After intratumor injection of hydrogen peroxide 0.5ml and sodium hyaluronate 2.5ml mixture once or twice per week, radiotherapy is give to tumor during four to six weeks. Simultaneously, intravenou
Sponsors
Kochi University, Kochi Medical School
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Inoperable metastatic melanoma 2) Be able to lie quietly for more than thirty minutes 3) SpO2 not less than 90% 4) Body temperature no more than 37.5 degrees 5) Gaining informed consent from patients or legal representatives
Exclusion criteria
Exclusion criteria: 1) Unable to secure infusion route of drugs by using ultrasound or CT 2) Determined to have high risk for bleeding by principalinvestigator or sub-investigators 3) Determined to have high risk for infection by principalinvestigator or sub-investigators 4) Determined to be inappropriate for this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The effect of tumor reduction is evaluated by diagnostic imaging at one month, two months and three months after end of treatment. Thereafter, every three months until two years later after treatment termination , and after that, once in six months. | — |
Countries
Japan
Contacts
Public ContactShigetoshi Sano
Kochi University, Kochi Medical School dermatology
Outcome results
None listed