Study of epigenetic control mechanism on skeletal muscle metabolism with total knee arthroplasty.

Study of epigenetic control mechanism on skeletal muscle metabolism with total knee arthroplasty. - DNA methylation of the skeletal muscle-related gene with total knee arthroplasty.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000026872

Enrollment

Registered

2017-04-05

Start date

2017-03-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis of the knee

Interventions

Total knee arthroplasty and rehabilitation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult person The consent patient who is performed total knee arthroplasty cause of osteoarthritis of the knee After receiving a full explanation upon participation in this study, through understanding, those documents consent free will of the person is obtained.

Exclusion criteria

Exclusion criteria: Patient of Cerebrovascular paralytic Patient of the nerve paralysis Patient of the nerve paralysis The patient who it is difficult to judge participation in study for a mental disease The other reason who principal investigator has determined to be inappropriate as a research subject.

Design outcomes

Primary

Measure	Time frame
The measure of skeletal muscle relation genes DNA methylation with osteoarthritis of knee patient.	—

Secondary

Measure	Time frame
The measure of Myokine with osteoarthritis of knee patient.	—

Countries

Japan

Contacts

Public ContactTomohiro Kamo

Kansai Medical University Hospital Health science

ryusei0819@gmail.com072-804-0101

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026