Clinical efficacy of FGLM-NH2+SSSR eye drops for intractable corneal epithelial disorders

Clinical efficacy of FGLM-NH2+SSSR eye drops for intractable corneal epithelial disorders - Clinical efficacy of FGLM-NH2+SSSR eye drops for intractable corneal epithelial disorders

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000026871

Enrollment

150

Registered

2017-04-06

Start date

2006-11-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

superficial punctate keratopathy persistent epithelial defect

Interventions

FGLM-NH2+SSSR eye drop 4 times a day Until disappearance of the epithelial defect Up to 4 weeks

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: intractable corneal epithelial disorders SPK: superficial punctate keratopathy (SPK) with fluorescein staining by slit-lamp examination PED: the presence of persistent epithelial defect by slit-lamp examination resistant to conventional treatments for more than 1 week

Exclusion criteria

Exclusion criteria: 1. Are pregnant or may possibly be pregnant 2. In breast-feeding women 3. Drug allergies for this agents 4. Were judged an inadequate subject to enrollment by a medical doctor

Design outcomes

Primary

Measure	Time frame
Time to complete healing for persistent epithelial defect	—

Secondary

Measure	Time frame
AD classification for SPK	—

Countries

Japan

Contacts

Public ContactNaoyuki Yamda

Yamaguchi University Graduate School of Medicine Department of Ophthalmology

n.yamada@po.cc.yamaguchi-u.ac.jp0836-22-2278

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026