Double-blind randomized parallel intergroup trial on the efficacy of the Lactobacillus rhamnosus L8020 containing gummi for oral health

Double-blind randomized parallel intergroup trial on the efficacy of the Lactobacillus rhamnosus L8020 containing gummi for oral health - Effect of Lactobacillus rhamnosus L8020 containing gummi on oral health

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000026727

Enrollment

Registered

2017-03-29

Start date

2017-03-29

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy people Patient with periodontal disease

Interventions

Volunteers ingest the L8020-containing gummi everyday for three months Volunteers ingest the placebo gummi everyday for three months

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Company staff member of MITSUI & CO., LTD. who receive dental checkups

Exclusion criteria

Exclusion criteria: 1. Subject with allergy to dairy products 2. Subject who receive dental treatments 3. Subject with desease effecting breath odor (Sjogren syndrome, Sinus inflammation, Systemic illness etc.) 4. Subject who intake L8020 containing products

Design outcomes

Primary

Measure	Time frame
Gingival index	—

Secondary

Measure	Time frame
Plaque index Breath odor Caries risk Periodontal status	—

Countries

Japan

Contacts

Public ContactNikawa Hiroki

Hiroshima University Department of Oral Biology & Engineering

hirocky@hiroshima-u.ac.jp082-257-5097

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026