Interstitial cystitis
Conditions
Interventions
Treated with vesical instillation with heparin and alkalized lidocaine. As introduction therapy, patients will recieve instillation every 1 to 2 weeks for six times. Then maintenance therapy follows w
Sponsors
Department of Urology, Mitsui Memorial Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients over 20 years old with interstitial cystitis who were diagnosed by hydrodistension at present institution. 2. Patients who are willing to participate in the study after written informed consent. 3. Patients with both OSSI and OSPI scores more than 6points and visual analogue scale for pain more than 3 points. 4. Patients who are able to be treated at outpatient.
Exclusion criteria
Exclusion criteria: 1. Patients who cannot fulfill the above inclusion criteria. 2. Patients with gross hematuria. 3. Patients with lidocaine allergy. 4. Patients who are regarded not suitable for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Global response assessment at 3rd month of maintenance therapeutic phase. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. daily urinary frequency, nocturnal urinary frequency, average voided volume per urination. 2. Maximum urine flow rate, average urine flow rate, residual urine volume. 3. O'Leary & Sant's symptom score, problem score, visual analogue scale for pain, overactive bladder symptom score, international prostate symptom score 4. adverse event at 6,12 the weeks after enrollment and 3rd,6th ,9th months at maintenance therapy. | — |
Countries
Japan
Contacts
Public ContactAkira Nomiya
Mitsui Memorial Hospital Department of Urology
Outcome results
None listed