non-small-cell lung cancer with idiopathic interstitial pneumonias
Conditions
Interventions
carboplatin with nab-paclitaxel
Sponsors
Kurashiki Central Hospital Department of Respiratory medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) chemotherapy-naive histologically or cytologically confirmed stage IIIA,B/IV (TNM classification 8th version)or postoperative recurrent NSCLC 2) without history of radiotherapy for primary tumor 3) more than and equal to 20 years old 4) diagnosed with idiopathic interstitial pneumonias 5) with measurable lesions of tumors 6) ECOG performance status of 0-2 7) with no highly disabled organ functions
Exclusion criteria
Exclusion criteria: 1) with interstitial pneumonias secondary to other conditions 2) with history of acute exacerbations of interstitial pneumonias within 3 months 3) with history of subacute exacerbations of interstitial pneumonias within 3 months 4) with usage of immunosuppressants 5) with peripheral neuropathy with Grade 2-4 6) with allergy to carboplatin, albumin, or taxane-based anticancer agents 7) with active infectious diseases 8) with active double cancers 9) with clinically important complications 10) with positivity of HBs antigen
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| response rate (not necessarily with confirmation) | — |
Secondary
| Measure | Time frame |
|---|---|
| progression free survival, overall survival, time to treatment failure, response rate with confirmation, adverse events | — |
Countries
Japan
Contacts
Public ContactToshihide Yokoyama
Kurashiki Central Hospital Department of Respiratory medicine
Outcome results
None listed