advanced esophageal and gastric cancer
Conditions
Interventions
only Diet Counseling
administration ONS once a day for 14 days
administration ONS twice a day for 14 days
administration ONS three times a day for 14 days
Sponsors
Cancer Institute Hospital Gastroenterological Chemotherapy Department
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)advanced gastric cancer or esophageal cancer 2)patients who plans 1st line chemotherapy or chemoradiotherapy 3)patients who can eat more than 50% 4)An age of over 20 5)PS ECOG performance status score 0-1 6)Major organs are in normal conditions in 14 days of administration neutrophil count => 1,500/mm3 Hemoglobin => 8.0g/dL Platelet count => 100,000/mm3 Serum bilirubin <= 1.5 mg/dL AST<=100 IU/L ALP<=100 IU/L Serum creatinine <= 2.0 mg/dL Written informed consent must be taken by patients
Exclusion criteria
Exclusion criteria: 1)ileus or subileus symptom 2)Active infectious diseases(except local infection) 3)massive ascites 4)weight loss more than 10% 5)plans triplet chemotherapy for 1st line chemotherapy 6)allergy for ONS 7)Uncontrollable DM 8)Pregnant or lactation women, or women with the possibility of the pregnancy 9)need systemic steroid therapy 10)Severe mental disorders, neurological disease 11)Dementia 12)Patients who are judged inappropriate for the entry into this study by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in the ratio of prealbumin before and after administration of ONS | — |
Secondary
| Measure | Time frame |
|---|---|
| Compliance of ONS, Changes in the ratio of various nutritional index before and after administration of ONS | — |
Countries
Japan
Contacts
Public ContactYukiko Izawa
Cancer Institute Hospital Department of Nutrition
Outcome results
None listed