Measurement of saliva drug concentration in patients undergoing cancer chemotherapy

Measurement of saliva drug concentration in patients undergoing cancer chemotherapy - Measurement of saliva drug concentration in patients undergoing cancer chemotherapy

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000026695

Enrollment

300

Registered

2017-03-30

Start date

2017-03-25

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal malignant tumor, Breast cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Adequate organ functiont 2.Psrformance status:0-2 3.Written informed consent prior to sutudy-spe cific screening procedure

Exclusion criteria

Exclusion criteria: Cannot collect saliva by oneself.

Design outcomes

Primary

Measure	Time frame
At the time of the intravenous feeding dosage end of the anticancer agent, We collect saliva seven days later for 72 hours for 24 hours. We measure the drug blood concentration of saliva which we collected qualitatively and quantitatively using liquid chromatograph - tandem type mass spectrometer (LC/MS/MS).	—

Countries

Japan

Contacts

Public ContactMotohiko Sano

Saitama Medical Center Saitama Medical University department of pharmacy

msano@saitama-med.ac.jp049-228-3599

Outcome results