Esophageal varices
Conditions
Interventions
The aims of the current study are to prospectively examine the safety and usefulness of DEX on sedation during prophylactic EIS for patients with EVs as compared with midazolam.
Sponsors
Hyogo college of medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients with liver cirrhosis (LC) (diagnosed by liver histology or radiologic findings) who will require prophylactic EIS for EVs. Presence or absence of past history for endoscopic treatments for EVs is not required. Causes of LC are not also limited. 2. Child 5 or 6 or 7 points.
Exclusion criteria
Exclusion criteria: Exclusion criteria 1.Poor liver function (Child-Pugh points of 8 or more) 2.Patients with severe comorbid diseases 3.Patients who were judged to be inappropriate for the study subjects
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| (a)Decreasing rate in SpO2 during endoscopic procedures (b)Increasing or decreasing rates in blood pressure during endoscopic procedures (c)Pulse fluctuation during endoscopic procedures (d)The rate of complications including disturbance or others (e)Ramsey Sedation Scale values | — |
Countries
Japan
Contacts
Public ContactYoshinori Iwata
Hyogo college of medicine Division of Hepatobiliary and Pancreatic disease, Department of Internal Medicine
Outcome results
None listed