Effect of oral appliance on short-term blood pressure variability in patients with obstructive sleep apnea.

Effect of oral appliance on short-term blood pressure variability in patients with obstructive sleep apnea. - Effect of oral appliance on short-term blood pressure variability in patients with obstructive sleep apnea.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000026601

Enrollment

100

Registered

2017-03-17

Start date

2017-03-17

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obstructive sleep apnea

Interventions

Observation of changes with OA therapy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Individual with mild to moderate OSA(5<AHI<30) Individual with normal occlusion Individual with more than 10 teeth in each of upper and lower jaw without severe caries and periodontal disease

Exclusion criteria

Exclusion criteria: Individual with refusing to cooperation Individual with already treated with CPAP Individual with disable to use OA more than four times a week Individual with starting hypertension treatment during this study Individual with temporomandibular disorders Individual with mental health problems

Design outcomes

Primary

Measure	Time frame
Apnea Hypopnea Index (AHI), LowestSpO2,blood pressure,short-term blood pressure,immunoreactive insulin(IRI),HbA1c	—

Secondary

Measure	Time frame
Subjective daytime sleepiness (JESS), Subjective sleep quality(PSQI)	—

Countries

Japan

Contacts

Public ContactMeiyo Tamaoka

Tokyo Medical and Dental University Sleep Modulatory Medicine

meiyo2.pulm@tmd.ac.jp03-5803-4967

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026