Healthy adults
Conditions
Interventions
Apply the formulation including an active ingredient to the one lower leg and the placebo to other lower leg twice daily for 4 weeks
Sponsors
Kao Corporation
Comprehensive Research Group
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: Healthy females
Exclusion criteria
Exclusion criteria: -Subjects with allergy for the skin care product -Subjects who are pregnant, planning a pregnancy, or breastfeeding - Subjects with a history of skin cancer, having active skin cancer, or who are receiving anti-cancer immunosuppressive treatments or medications -Subjects with a history of immunosuppression/immune deficiency disorders (including (HIV infection or AIDS) or currently using immunosuppressive medications and/or radiation as determined by study documentation One with the plan to receive a medical act during study period -Subjects currently participating in, or scheduled to participate in, any medical trial, consumer study, or any other clinical study on the body during the study period. -Subjects who has caused abnormalities in the test site in a past similar study -Subjects who takes hormone replacement therapy, or are on hormonal birth control -Subjects who takes medical supplies (insulin, steroid, immunosuppressive drug) which may have an influence on the results -Subjects deemed inappropriate to participate in this study by the principle investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change of water content, transepidermal water loss, visual score and texture before and after the topical application for 2, 4 and 5weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Change of cell morphology and the composition of stratum corneum before and after the topical application for 2, 4 and 5weeks | — |
Countries
North America
Contacts
Public ContactTakatoshi Murase
Kao Corporation R&D -Core Technology-Biological Science Research
Outcome results
None listed