Pancreatic Cancer
Conditions
Interventions
Heavy-ion Particle Radiotheray 55.2Gy(RBE)/12fr/3weeks
Sponsors
National Institutes of Quantum and Radiological Science and Technology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Locally recurrent pancreatic cancer in patients with prior carbon-ion radiotherapy 2)No invasion on the digestive tract. 3)Radiographically no ascites at upper abdomen 4)Unresectable or refusal to receive operation 5)radiographically measurable tumor, 6)No evidence for metastatic disease or resectable metastatic disease 7)Age older than 19years 8)performance status of 0-1 9)signed an informed consent form
Exclusion criteria
Exclusion criteria: 1) clinical target volume (CTV) t>15 cm 2)Placement of a metal stent for relief of biliary obstruction (metal stents may be placed following completion of radiation therapy). 3)received chemotherapy within 2 weeks of CIRT 4)had an open or active infection at the tumor site; 5)had another primary malignancy 6)severe complication 7)Expected medical intolerance of clinical research because of mental disorders
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of grade 3-5 acute toxicity | — |
Secondary
| Measure | Time frame |
|---|---|
| overall survival,local control rate Rate of grade 3-4 late toxicity | — |
Countries
Japan
Contacts
Public ContactShigeru Yamada
National Institutes of Quantum and Radiological Science QST Hospital
Outcome results
None listed