Healthy adults
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy female aged from 25 to 39 years old. 2. Person who have been feeling stressed for one or two months. 3. Person who worry the cold of hand and foot. 4. Person who have clear scaling and whose stratum corneum water content are low on the face. 5. Person whose menstrual cycles are from 25 to 30days. 6. Person whose body math indexes are from 18.5 or more to 25 less than 25.0. 7. Person whose diastolic blood pressures are less than 90mmHg and systolic ones less than 140mmHg. 8. Person who can agree to participate in the study voluntarily in writing. 9. Person who can agree not to ingest foods and supplements for beauty during the test period.
Exclusion criteria
Exclusion criteria: 1. Person who has abnormalities in the skin of the measurement region 2. Person who regularly goes to hospital. 3. Person with the anamnesis of an alcohol or drug dependence. 4. Person who regularly use drug (hypnotic drug, anti-allergic drug, analgetic drug, hormonal drug, laxative, antiflatulent etc..). 5. Person who has possibilities for emerging allergy to cosmetics and/or foods (including experiences of skin irritation by cosmetics within a year). 6. Person who has allergy to adhesive tape and/or medical tape. 7. Person who suffers pollen allergy, rhinitis and atopic dermatitis. 8. Person who is pregnant or lactating, or planned to become pregnant during a test period. 9. Person who participates in the other clinical studies within 4 weeks in the past, or person who scheduled to participate in other clinical studies during the test period. 10. Person who is judged as unsuitable for the study by the investigator for other reasons. 11. Person who herself and/or her family member are working for the cosmetics company, the food company, an advertising agency, investigation and consultant business, and a mass media-related company. 12. Patient with vascular function disorder, or person who has excessive sensitivity to cold. 13. Person who has abnormal blood pressure or electrocardiogram testing result. 14. Current smoker. 15. Person who experienced medical cosmetic treatment (i.e. cosmetic surgery, collagen injection etc..)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of the stratum corneum water content, transepidermal water loss, the amount of lactate acid and blood flow measurement after ingestion of a beauty beverage containing plant extracts | — |
Countries
Japan
Contacts
Kao Corporation R&D Skin Care Products Research