Healthy person
Conditions
Sponsors
Beauty & Health Research Inc
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1)Those who received a sufficient explanation of the purpose and contents of this exam, who have the capacity to consent, voluntarily volunteer with sufficient understanding, and agree to participate in the document 2)A healthy woman aged 20 years or under and under 50 years old who satisfies the following conditions at screening (1) Persons whose stool frequency is 4 or less on average per week
Exclusion criteria
Exclusion criteria: Not applicable to any one of the following exclusion criteria. 1) Currently, those who have some type of chronic illness and are undergoing drug treatment 2) Persons who are allergic to chocolate, milk, soybeans 3) Headache induced by ingestion of chocolate 4) Persons with lactose intolerance 5) Those who take cocoa products four times a week or more during the three months before screening 6) Those who take natto at least four times a week for three months before screening 7) Those who ingest lactic acid bacteria-containing foods such as yoghurt, lactic acid bacteria beverages and the like more than four times per week for three months before the screening 8) Persons taking or ingesting medicines such as intestinal medicines, which may affect this test result, quasi-drugs, supplements, health foods, foods for specified health use (Tokuho), functional display foods on a daily basis, Or who intends to take or ingest during the test 9) Those who participated in other clinical trials and monitoring examinations during the month before screening, or who plan to participate in other clinical trials after this clinical trial consent 10) Persons who are pregnant, plan for pregnancy during the study period, those who have hope 11) Who is breastfeeding 12) Alcohol-heavy drinkers (drinkers with a daily average over 60 g in terms of pure alcohol) 13) Others who judged that the investigator is inappropriate as the subject
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)Bowel movement (stool frequency, stool volume) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Bowel movements (defecation days, feces) 2) Blood short chain fatty acid concentration (HPLC method) 3) Fecal acid short-chain fatty acid concentration (HPLC method) 4) Faecal bacteria and fecundity in faecal bacteria (qPCR method) 5) Relief of constipation (CAS method; Japanese constipation rating scale) | — |
Countries
Japan
Contacts
Public ContactAi Marume
Beauty & Health Research_Inc Medical Research Department
Outcome results
None listed